50 Yr Male Came with C/O B/L knee pain since 1 year

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50 yr Male Farmer By Occupation  Came to Casualty With Cheif Complaints Of Bilateral Knee Pain since 6 days

HOPI :-
Patient Was Apparently Asymptomatic 4 years Back , Then He Developed Bilateral Knee joint Pain ( Insidious In Onset, Gradually Progressive ) On & off , went to Rural Community Practisioner And Given Medicine , The Patient Had Been Taking pain management Medication when he has Joint Pain . Swelling was also present at the knee and Ankle joints during during Pain . The patient was abke to do his Routine farming Activities for 2 years .

Since 2 years the patient stopped  doing  farming works and used to stay at home and was able to take care of his own . When patient has pain he used to take rest and On severe pain patient used to take medication given by rural community Practisioner. Pain was not completely releived On taking medication but patient used to feel better.
The pain was aggravated since 1 week and the patient was unable to walk , bear weight , take care of himself and was admitted in our Hospital , Diagnosed with Hyperurecemia & Dimorphic Anemia .

In Hands : Pain Initially Starts In the wrist , swelling apears ( flexion occurs at metacarpal-phalanges joint ) for 1-2 days , and pain Migrates to the elbow ( Unable to Flex completely , Swelling + ) for 2 days and then pain Migrates to shoulder ( unable to lift, abduct the Shoulder). and then the other hand involves 

Pain Is Assymetrical ( when one hand is involves the other is not involved )

In Legs :  pain initially gets started in the ankle joint ( Swelling + , duration 1-2 days ) and pain Migrates to knee ( unable to bear weights , walks with the help of stick/ support , swelling + , duration 1-2 days ) and then the pain Migrates to the Hip joint 

Pain Is Assymetrical ( when one leg is involves the other is not involved )


No C/O Diarrhoea & Vomitings

No C/O Shortness of Breath , Palpitations , Ornthopnea ,PND

Not a Known Case of DM, HTN ,TB , Epilepsy , Asthma

No Similar Complaints in the Past

Family History
No Similar Complaints In the family

Personal History :
1) Alcohol : Used to consume Toddy twice a week 6-7 years Back .Now Completely Stopped Consuming Alcohol

Appetite Decreased
Bowl & Bladder movements Normal
Food : mixed , since 3-4 years back stopped consuming chicken & meat

GENERAL EXAMINATION

NO Icterus , Cyanosis , Clubbing ,lymphadenopathy.

PALLOR +

Vitals 
Temp   - afebrile
BP       - 100/60 mm hg 
PR       - 82 bpm. 
RR       - 19 cpm 
spo2  100 @RA 
GRBS  - 158 mg/dl @ 8 am
CVS    - S1, S2 heard 
RS      - bae present 
P/A    - soft , tender , Guarding Present
CNS   - NAD


Examination Of Joints 

Wrist joint : Partial Movement of flexion and extension approximately 30-45 degrees
Swelling + at Wrist joint

Fingers  : unable to completely flex phalanges, Stifness +

Knee & ankle joint : Unable to flex completely  , but can flex  upto 30 degrees 
Swelling + , Stiffness +

Elbow : can flex and Extend Normally

Shoulder  : can lift shoulders above the head but not 180 degrees at shoulder Joint.
During pain unable to lift the bucket 


INVESTIGATIONS

HAEMOGRAM

Haemoglobin   - 4.6 
Total Count      - 10,200 cells / cumm
Rbc                    - 1.76 million / cumm
Platelet Count  - 2.40 lakhs

Reticulocyte Count   -  0.8 %
ESR                             - 150
RA Factor                   - Negative

Peripheral Smear :
RBC Normocytic normochromic with few microcytes tear drop cells pencil forms

WBC With in normal limits absolute neutrophilia

PLATELET Adequate

Synovial Fluid
Sugar        - 140 mg/dl   ( 60-100 mg/dl)
Protein      - 4.2 mg/dl    ( 10-45 mg/dl )
Uric Acid   - 10.7 mg/dl  ( 10.7 mg/dl )

Synovial Fluid Cell Count 
Colour           - Yellowish
Appearance  -  Cloudy
Total Count   - 29000 cells
Monocytes     - Nil
Neutrophils    - 95 %
Lymphocytes  - 05 %
RBC                  - Nil

LDH                 - 240 IU/L


RFT

Blood Urea      - 56
S Creatinine    - 1.6
S Uric Acid      - 
Na                    - 130
K                      - 3.7
Cl                     - 92

CRP                 - Negative

ApTT           - 31 sec
PT               - 15 sec
INR              - 1.11


Blood Group - B Positive

Synovial Fluid Cytology 



XRay


ECG

2D Echo


PROVISONAL DIAGNOSIS
Anaemia Under Evaluation with ? Iron Deficiency Anemia with Rheumatoid Arthritis  ( seronegative ) with Hyperurecemia


Treatment 
1) Inj Monocef 1 gm IV / BD
2) Tab Methotrexate 7.5 mg / PO Weekly Once 
3) Tab Folvite 5 mg / PO weekly Once
4) Tab Prednisolone 10 mg / PO / OD
5) Tab Colchicine 0.5 mg PO/BD


SOAP NOTES 
Ward Day 3

S

C/o Pain B/L Knee Joint Pain Decreased
 

O - Patient is conscious,coherent,cooperative.

Now Patient Is Able to walk after aspirating 15-18 ml of Synovial fluids from both the legs on 17/03/2022

vitals :

Temp - afebrile
BP - 120/80 mm hg 
PR - 90 bpm. 
RR - 18 cpm 
spo2 - 100 @RA 
GRBS - 
CVS - S1, S2 heard 
RS - bae present , 
P/A - Soft , non tender
CNS - NAD


A - Anaemia Under Evaluation with ? Iron Deficiency Anemia with Rheumatoid Arthritis ( seronegative ) with Hyperurecemia

P -
1) Inj Monocef 1 gm IV / BD
2) Tab Methotrexate 7.5 mg / PO Weekly Once 
3) Tab Folvite 5 mg / PO weekly Once
4) Tab Prednisolone 10 mg / PO / OD
5) Tab Colchicine 0.5 mg PO/BD


Ward Day 4

S
C/o Pain B/L Knee Joint Pain Decreased
 

O - Patient is conscious,coherent,cooperative.

vitals :
Temp - afebrile
BP - 120/90 mm hg 
PR - 85 bpm
RR - 16 cpm 
spo2 - 99%@RA 
CVS - S1, S2 heard 
RS - bae present , 
P/A - Soft , non tender
CNS - NAD

A - Anaemia Under Evaluation with ? Iron Deficiency Anemia with Rheumatoid Arthritis ( seronegative ) with Hyperurecemia

P -
1) Inj Monocef 1 gm IV / BD
2) Tab Methotrexate 7.5 mg / PO Weekly Once 
3) Tab Folvite 5 mg / PO weekly Once
4) Tab Prednisolone 10 mg / PO / OD
5) Tab Colchicine 0.5 mg PO/BD



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